News 920 views update:Mar 9, 2016

Suppressing Salmonella Arizonae and Salmonella Heidelberg

The intestinal microbial fermentation of poultry may be preferentially shifted to suppress growth of the pathogens Salmonella Arizonae (SA) and Salmonella Heidelberg (SH) by Original XPC, according to research using an in-vitro poultry intestinal model.

Two experiments were conducted. In the first, the level of acetate, butyrate and total volatile concentrations increased in vitro in conjunction with the inclusion of Original XPC, and the growth of SA was suppressed significantly. In the second experiment, the concentrations of acetate, propionate, butyrate and total volatile fatty acids (VFA) likewise increased, and the growth of SH was suppressed significantly.

The research was presented as a poster at the recent annual Poultry Science Association meeting. Previous research demonstrated suppression of Salmonella Enteritidis (SE) in conjunction with Original XPC. Original XPC is manufactured and marketed by Diamond V, the world’s leading supplier of all-natural, microbial, fermentation-based feed additives.

Increased concentrations of VFA in the small intestines has been linked through research to reduced colonisation by pathogens such as Salmonella. The VFA butyrate is of particular interest in animal agriculture because feeding butyrate has multiple known benefits to gut and overall health. Most notable among these are attenuation of the inflammatory response, suppression of pathogen growth, and morphological improvements in the intestinal mucosa. Recently research showed that adding exogenous butyrate to an in vitro intestinal model challenged with Salmonella Typhimurium (ST) resulted in inhibition of ST growth.

The experiments presented at the PSA meeting had similar methodology. Under anaerobic conditions, predigested turkey diet was combined with fecal inoculum and either a control grain or Original XPC. The test tubes were challenged with either SA or SH and were then incubated after which the contents were analyzed for VFA by gas chromatography. The test was replicated five times in the SA experiment, 10 times in the SH experiment.

In the SA experiment, intestinal microorganisms were sourced from the fresh excreta of 10 young turkeys, and SA was originated with a young turkey in a commercial operation with re-occurrence problems. In the SH experiment, the intestinal microorganisms were sourced from the fresh excreta of 12 laying hens; SH originated with a human being with an egg-associated illness.

World Poultry

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