Mar 5, 2008

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MG-related problems in the poultry industry

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Mojtaba Yegani Function: Blogger Mojtaba Yegani received his DVM degree from faculty of Veterinary Medicine of University of Tehran, Iran.

Mycoplasma gallisepticum (MG) infection will likely continue to persist in poultry, especially in broilers, broiler breeders, and commercial layers in many parts of the world. This is an indication that eradication efforts have not been completely successful so far.

In the period after infection, the organism is present in the respiratory tissues in high levels and is shed into the environment and eggs. The infection persists in the flock for a long time. However, the organism is very fragile and can live outside the chicken for only a few days and is easily killed by disinfection.

Although biosecurity measures are very important, use of antibiotics and vaccines are also among the strategies which may reduce the adverse affects of MG infection in commercial farms.

I. Depending on your workstation (broilers, broiler breeders, commercial layers), how is the magnitude of MG-related problems in your farm?
II. Do you think that use of antibiotics is still the most practical way to manage this infection?
III. How promising do you see preventive effects of vaccination?
VI. How about using a combination of antibiotics and vaccines?

by Mojtaba Yegani Mar 5, 2008

9 comments

dr eid soliman Mar 5, 2008

# 1

firstly we all know the economic importanc of MG as one of the costlist disease problem in poultry indusry,causing CRD and mortality from5-30% in broiler, 1-2%monthly in layers with egg losses 15/egg/hen and 5%decrease in hatchability rate with late embryonic death.My PH.D was in evaluation of mycoplasma vaccines in poultry farms and my conclusion was using of bactern with antibiotic treatment when infection is diagnosed,this will decrease the shedding of mycoplasma to day old chicks.
yours
dr: eid soliman
researcher,mycoplasma dep. animal health research institute cairo Egypt

dr.mohammad Al-nawasrha Mar 7, 2008

# 2

the best control of MG in the broilers by using antibiotics.in the first 3 day use the tylosin then in 20 day use doxycycline for 5 days

Juan Carlos Franco Mar 7, 2008

# 3

Hi

I like more information about using a combination of antibiotics and vaccines. I work in Dominican Republic with commercial layers for control of MG and MS.
Sincerely,

Dr Gima Elhafi Ph,d animal health director Mar 10, 2008

# 4

no vaccination and /or medication program can prevent infection or eleminate carrier state.
vaccination and medication programs only:
Reduce shed quantity.
Reduce shed duration.
increased challenge required to infect

DR. S. S. MANN , INDIA Mar 15, 2008

# 5

it depends on history & severity .
in breeders can be controlled by vaccination .
in broilers - give first 3 days Pulmotil ( ELANCO product )@ 3.5 ml / 1000 birds & repeat at 21 & 22 days @ 30 ml / 1000 birds , in addition support thr. feed with Tylosine phosphate ( 10% )@ 1000gms / ton & ctc ( 15% ) @ 1000 gms./ ton of feed regularily .
for layers by using Tylosine tartrate (raw ) @ 8 gms/1000 birds for first 3 days & support it with Tylosine phosphate & ctc thr. feed regularily .

lokman Taib Mar 15, 2008

# 6

In my country this is very big problem specillay in 1998 and also in 2003 we lost larg number of broiler becuase this disease is occur as outbreak and antil now we use at first three day Tylosin and reated at 30day but we need more to prevent this problem

DMV KADI r Mar 16, 2008

# 7

audemmarage ;TILMICOSINE pendant 3jours arenouvler le25jour,, oubienet encas d'accident association de la FLUMEQUINE A50/ et ENROFLO//MERCI DMV KADI /KADI AVICOLA/ALGERIE /

Dr.Rajendra Kumar Mar 16, 2008

# 8

MG is an chronic infestation. There are combination of factors which trigger and sustain the infection to remain viable and spread from one flock to the next. Some of the causes are :
1. Poor biosecurity measures
2. High dust levels
3.Secondary infections like E.Coli, IBD, Infectious Coryza
4.Over crowding.
5.Close proximity to other farms
6.Multiple age groups.
Tackle these problems with proper balanced diet, MG bacterins and medication will reduce the problem and in the long run control the problem at a site.

Dr. Ilker HOSGOR Oct 26, 2010

# 9

Hi, i would like take attention on MS rather than MG. I have been working and studying the mycoplasm problem in field level for nearly three years, consultant veterinarian. First of all i should state that my findings are limited over a region, not to mention any scientific finding.
Well, MS is shed and hides until the flock meets a really hard situation, a stress factor -change in feeding or the feed texture, heat and/or cold stress better say sudden climate changes- besides this may also depend on an outbreak of a virus or bacterial infection. Hence we vaccinate the layers every 30-35 days via La Sota, we did not encounter ND problem, titers more than enough.. A flock for instance 95% positive MS -PCR findings- may not show any sign(s). We can get the objective number of eggs; probably just a little break between 80-90% of lay. We faced MS through 50-55 weeks of age, without recognized increase of mortality and soft/thin shelled eggs, of course a slight increase but still will not need any cure. The typical finding would be in egg production, it may fall 6-12% in 3-4 weeks. Post mortem findings do not seem typical of a disease but egde of the beak is mostly blueish in color and may seem like to fade or little bit dry in consistency. According to my examination i mostly met with some white cheese like liquid-exudate over the ovary, uterus and fluid in dissection of the uterus. Enlargement of the liver and spleen are mostly common. Swelling of the hock joint or the articulate would be rare, but leads to a certain decision.
A contamination with E. coli will harden the diagnosis and treatment of the situaiton. Another opinion of miane will be the answer to either tylosin or tiamulin. In general the laying rate jumps on the second day in hens aged around 50-60 weeks or the third day when older then 70 weeks of age. Hard to decide but instead of treatment forced molting may also help to improve..
In treatment Denegard (Tiamulin) of Novartis company helps to avoid economic losses, 400-600ppm 5-6 days and a reasonable continuous dose following the treatment.
I will be glad if these findings help anyone in business.
Yours
Dr. Ilker HOSGOR

dr eid soliman Mar 5, 2008

# 1

firstly we all know the economic importanc of MG as one of the costlist disease problem in poultry indusry,causing CRD and mortality from5-30% in broiler, 1-2%monthly in layers with egg losses 15/egg/hen and 5%decrease in hatchability rate with late embryonic death.My PH.D was in evaluation of mycoplasma vaccines in poultry farms and my conclusion was using of bactern with antibiotic treatment when infection is diagnosed,this will decrease the shedding of mycoplasma to day old chicks.
yours
dr: eid soliman
researcher,mycoplasma dep. animal health research institute cairo Egypt
dr.mohammad Al-nawasrha Mar 7, 2008

# 2

the best control of MG in the broilers by using antibiotics.in the first 3 day use the tylosin then in 20 day use doxycycline for 5 days
Juan Carlos Franco Mar 7, 2008

# 3

Hi

I like more information about using a combination of antibiotics and vaccines. I work in Dominican Republic with commercial layers for control of MG and MS.
Sincerely,
Dr Gima Elhafi Ph,d animal health director Mar 10, 2008

# 4

no vaccination and /or medication program can prevent infection or eleminate carrier state.
vaccination and medication programs only:
Reduce shed quantity.
Reduce shed duration.
increased challenge required to infect
DR. S. S. MANN , INDIA Mar 15, 2008

# 5

it depends on history & severity .
in breeders can be controlled by vaccination .
in broilers - give first 3 days Pulmotil ( ELANCO product )@ 3.5 ml / 1000 birds & repeat at 21 & 22 days @ 30 ml / 1000 birds , in addition support thr. feed with Tylosine phosphate ( 10% )@ 1000gms / ton & ctc ( 15% ) @ 1000 gms./ ton of feed regularily .
for layers by using Tylosine tartrate (raw ) @ 8 gms/1000 birds for first 3 days & support it with Tylosine phosphate & ctc thr. feed regularily .
lokman Taib Mar 15, 2008

# 6

In my country this is very big problem specillay in 1998 and also in 2003 we lost larg number of broiler becuase this disease is occur as outbreak and antil now we use at first three day Tylosin and reated at 30day but we need more to prevent this problem
DMV KADI r Mar 16, 2008

# 7

audemmarage ;TILMICOSINE pendant 3jours arenouvler le25jour,, oubienet encas d'accident association de la FLUMEQUINE A50/ et ENROFLO//MERCI DMV KADI /KADI AVICOLA/ALGERIE /
Dr.Rajendra Kumar Mar 16, 2008

# 8

MG is an chronic infestation. There are combination of factors which trigger and sustain the infection to remain viable and spread from one flock to the next. Some of the causes are :
1. Poor biosecurity measures
2. High dust levels
3.Secondary infections like E.Coli, IBD, Infectious Coryza
4.Over crowding.
5.Close proximity to other farms
6.Multiple age groups.
Tackle these problems with proper balanced diet, MG bacterins and medication will reduce the problem and in the long run control the problem at a site.
Dr. Ilker HOSGOR Oct 26, 2010

# 9

Hi, i would like take attention on MS rather than MG. I have been working and studying the mycoplasm problem in field level for nearly three years, consultant veterinarian. First of all i should state that my findings are limited over a region, not to mention any scientific finding.
Well, MS is shed and hides until the flock meets a really hard situation, a stress factor -change in feeding or the feed texture, heat and/or cold stress better say sudden climate changes- besides this may also depend on an outbreak of a virus or bacterial infection. Hence we vaccinate the layers every 30-35 days via La Sota, we did not encounter ND problem, titers more than enough.. A flock for instance 95% positive MS -PCR findings- may not show any sign(s). We can get the objective number of eggs; probably just a little break between 80-90% of lay. We faced MS through 50-55 weeks of age, without recognized increase of mortality and soft/thin shelled eggs, of course a slight increase but still will not need any cure. The typical finding would be in egg production, it may fall 6-12% in 3-4 weeks. Post mortem findings do not seem typical of a disease but egde of the beak is mostly blueish in color and may seem like to fade or little bit dry in consistency. According to my examination i mostly met with some white cheese like liquid-exudate over the ovary, uterus and fluid in dissection of the uterus. Enlargement of the liver and spleen are mostly common. Swelling of the hock joint or the articulate would be rare, but leads to a certain decision.
A contamination with E. coli will harden the diagnosis and treatment of the situaiton. Another opinion of miane will be the answer to either tylosin or tiamulin. In general the laying rate jumps on the second day in hens aged around 50-60 weeks or the third day when older then 70 weeks of age. Hard to decide but instead of treatment forced molting may also help to improve..
In treatment Denegard (Tiamulin) of Novartis company helps to avoid economic losses, 400-600ppm 5-6 days and a reasonable continuous dose following the treatment.
I will be glad if these findings help anyone in business.
Yours
Dr. Ilker HOSGOR