News 5386 views 1 commentupdate:Mar 9, 2016

Essential oils key in fight against antibiotic use

Essential oils are a key solution to an alternative for antibiotic growth promoters (AGPs), this was shown by research carried out by US food giant, Cargill. But what do essential oils achieve that other non-medicated feed additives don’t?

As an independent supplier, the company performed cross-additive research and determined the most beneficial types of feed additives for individual customer needs. For consistent performance improvement, essential oils turned out to be a key solution because they impact all 4 key gut function areas.

Essential oils key in gut health support

Gut health is important in poultry production because the digestive system performs key functions essential to ensuring birds' optimum performance. The optimal gut function in 4 key areas are:

  1. Managing microflora for a well-balanced bacterial population
  2. Controlling immune function and inflammatory response
  3. Maximising nutrient digestion and absorption
  4. Improving the physical barrier against pathogens

While all additives studied showed some benefit in these areas, Cargill researchers found that selected essential oil compounds, particularly those derived from thyme, cinnamon and oregano, had the most comprehensive effect on overall gut health. Benefits included antimicrobial activity, modulation of immune response, antioxidant activity, improvement of nutrient digestibility and stimulation of mucus production.

"Activity against pathogens"

"Only essential oils have both a broad spectrum of activity against pathogens and a direct impact on digestive function," said Stephanie Ladirat, global technology lead for gut health additives in Cargill's animal nutrition business.

Also interesting: Worrying increase in antimicrobial drug use in US livestock

Domestic sales and distribution of antimicrobials approved for use in food producing animals in the US increased by 22% from 2009 through 2014. This is stated in the latest FDA report on this topic.

Since 2009, a combined total of 77 comprehensive in vitro and in vivo trials have been conducted at Cargill's Animal Nutrition Innovation Centers in Velddriel, the Netherlands, and Elk River, Minn., as well as at regional facilities in Jordan, France, Poland, India and the US, on additives including essential oils, probiotics, yeast derivatives and medium chain fatty acids (MCFA).

Essential oils role in antibiotic reduction

Essential oils were found to be particular efficient in conditions where intestinal infections such as Salmonellosis and Coccidiosis were present. They were also found to be a viable alternative to antibiotics as more than 85% of the results showed a minimal difference between the positive control (antibiotics) and essential oils.

Also interesting: Battling coccidiosis with vaccinations

Coccidiosis in broiler flocks can be tackled by administering anti-coccidials. However, resistant coccidiosis can render coccidiostats almost useless. That was the case at Tom Serraerens broiler farm in Belgium. Using a vaccine was his last resort.

The research also showed that essential oils are just one facet of a feeding programme that promotes ideal gut health and allows antibiotic reduction. Research findings support combining essential oils with organic acids to get maximum efficacy. "Cargill's local nutrition experts are working directly with poultry producers to develop customised, holistic feeding programmes encompassing nutrition, additives and farm management based on the study results," says Twan Van Gerwe, poultry R&D director in Cargill's animal nutrition business.

Feed conversion trials

Combined study results from 12 trials demonstrated that birds given Cargill's Promote Biacid Nucleus additive, which contains a proprietary mixture of 7 carefully selected essential oil compounds, in combination with an antibiotic-free diet, consistently improves body weight gain by 2% and feed conversion by 1.5%, producing a return on investment (ROI) of 5:1 for producers.

One comment

  • Luc Goethals

    Everybody will acknowledge the leading position of CARGILL in world animal nutrition and many might know the Provimi research unit in Veldriel. No argument to contest.
    On the contrary, it might not be fully correct to state the "indepency" of the research, as both Cargill and Provimi are commercial operations. Opposite to what is suggested, most herbal based products have failed to show consistent results for many reasons and claimed modes of actions have been questioned in many peer review studies at independent research bodies. Dosage and levels of the used herbal sustances most of the time are 100-1000 fold below MIC-value for antimicrobial effect. Many are pro-inflammatory, at least in vitro. A pH-D study at Ghent University show even negative effects on digestion and absorption and many substances decrease oral tolerance at intestinal level.
    So things are not so simple and linear as presented.

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