Also known as Polyneuritis, Thiamin deficiency /Vitamin B1
Vitamin B1 / Thiamin deficiency occurs worldwide in poultry of all ages. It is caused by deficiency of Vitamin B1 / Thiamin Amprol excess in the diet or can be caused by moldy feed or by rancid fat oxidation. Deficiency takes 3 weeks to develop.
- Causes of Vitamin B1 / Thiamin deficiency >
- Effects of Vitamin B1 / Thiamin deficiency >
- Diagnosis of Vitamin B1 / Thiamin deficiency >
- Treatment & Control of Vitamin B1 / Thiamin deficiency >
Causes of Vitamin B1 / Thiamin deficiency
Vitamin B1 is needed for formation coenzyme involved in proper nervous system function. This disease can affect all species of bird. It takes 3 weeks for the deficiency to develop.
Mode of transmission
Vitamin B1 (thiamine) deficiency or excess can be caused by amprol feed moldy or rancid fat by oxidation. Thiamine is converted in the body to an active form, thiamine pyrophosphate, which is an important cofactor in oxidative decarboxylation reactions and alder exchanges incarbohydrate hyde metabolism.
Effects of Vitamin B1 / Thiamin deficiency
Nervousness, anorexia, ruffled feathers, leg weakness and an Unsteady gait can occur. Paralysis (convulsions with head retraction) called polyneuritis and star-gazing (head retracted due to paralysis of the anterior muscles of the neck) can occur in young birds. Adults may have a blue comb, a decrease in respiration rate and lowered body temperature.
Post mortem lesions
Hypertrophy of adrenal glands, cortex and medulla from Accumulate edema, atrophy of the gonads, stomach and intestinal walls are evident.
Diagnosis of Vitamin B1 / Thiamin deficiency
Clinical signs and histopathology are helpful. Microscopically dilated crypt or Lieberkühn occur in the duodenum. Exocrine pancreatic cells or show cytoplasmic vacuolation and hyaline body formation.
It Simulates Avian encephalomalacia, Vitamin E deficiency and Newcastle disease.
Treatment & Control of Vitamin B1 / Thiamin deficiency
Prevention
Quality control of the feed. A correct level drug will help prevent the disease.
Treatment
Alter the B1 level or drug level in the feed. Since most grains are high in B1, it does not need to be added to the diet. Amprol, a common anticoccidial mediation, can bind thiamine.
